Foundation for the National Institutes of Health (FNIH) | April 7, 2017

Fostering Worldwide Collaboration to Fight Alzheimer鈥檚 Disease

Twenty five years ago, Michael W. Weiner, M.D., decided to make it his life’s mission to find a treatment for Alzheimer鈥檚 disease. 鈥淚 had to choose one disease to focus on, because in science that鈥檚 the way you have the most impact and it was a very deliberate decision to go after Alzheimer鈥檚. It was obviously a disease of great importance with a lot of people affected.鈥

More than five million 精东影业ns suffer from this progressive brain disorder. According to the Centers for Disease Control and Prevention, Alzheimer鈥檚 disease is the sixth leading cause of death in the United States. It is almost certain that all 精东影业ns will know someone who is affected by the disease, or is diagnosed themselves. It is a painful experience for everyone involved, emotionally and financially. The symptoms range from memory damage to hallucinations, which can translate into a loss of independence and even self-identity. 鈥淵ou may have a grandparent now who can鈥檛 manage their own finances, or who can鈥檛 shower on their own independently,鈥 explains Dr. Weiner. 鈥淚t is a big problem with huge costs to society.鈥 听

With the number of people suffering from Alzheimer鈥檚 disease expected to triple by 2050, Dr. Weiner鈥檚 research has never been more critical. He has served as the Principal Investigator of the since its launch 12 years ago, when the National Institute on Aging and the private sector, lending support through the , funded the study. A first-of-its-kind partnership between the federal and the private sectors in Alzheimer鈥檚 disease, ADNI brings together scientists and leaders from academia, biomedical companies and not-for-profit organizations to uncover the biological markers (biomarkers) that track disease progression. The study, now in its third incarnation after consistently being renewed and expanded, uses imaging, biochemical and genetic data to identify changes taking place in the brains of 800 individuals with normal cognition and at different stages of disease. Most significantly, the data are made immediately available to any researcher at any organization. This means no one 鈥渙wns鈥 the study鈥檚 data, and researchers worldwide can use them to publish papers and lay the groundwork for further discoveries.

ADNI is revolutionizing the way scientists study and understand Alzheimer鈥檚 by helping to define its earliest stages before clinical symptoms appear and by sharing data with scientists as they are collected. The data have been downloaded for research purposes more than 14 million times and used to publish more than 1,200 scientific papers. 鈥淪omeday when there are successful treatments for Alzheimer鈥檚 disease all of us are going to know that it was done, in part, because of ADNI data.鈥澨

You can help the FNIH advance critical research for diseases such as Alzheimer鈥檚. Make a donation to support ADNI by or learn more about FNIH giving opportunities . 听


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